Immunodeficiency Diseases

In healthy individuals, the immune response comprises two phases. The first phase of defence is the Natural immune response (innate immune) system, which does not allow any micro-organism to enter the body. This will also destroy the infection alone but usually; the Natural immune response will contain the infection long enough for the adaptive immune (Acquired immune) system to activate. The adaptive response is the second line of defence and takes several days to assemble. The response is specific to the microbe and leaves a lasting immune memory, which makes the response to act immediately when it senses the visit of the same infectious disease. In a person with an immunodeficiency disorder, one or more components of either the adaptive or Natural immune response is impaired, resulting in the body being unable to effectively resolve infections or disease. This leaves immunodeficient individuals at high risk of recurrent infection and exposed to conditions that would not usually be of concern to otherwise healthy individuals

  • Track 1-1 Chronic Granulomatous Disease
  • Track 2-2 Wiscott-Aldrich Syndrome
  • Track 3-3 DiGeorge Syndrome
  • Track 4-4 Agammaglobulinemia

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